Moxibustion increases the number of ovarian granulosa cells Moxibustion increases the number of ovarian granulosa cells: Our results showed that mild warm moxibustion (MWM) modulated the circulating levels of estradiol and follicle-stimulating hormone and their receptors and inhibited apoptosis in the ovaries, similar to the effect of estrogen. Further investigation revealed that the effects of MWM on ovary tissues and cultured GCs were mediated by the modulation of the activity of Forkhead box protein O1 and involved the JAK2/STAT3 pathway. Reference Shi et al. (2015) Moxibustion Reduces Ovarian Granulosa Cell Apoptosis Associated with Perimenopause in a Natural Aging Rat Model. Evid Based Complement Alternat Med: Article ID 742914. doi: 10.1155/2015/742914.