Chinese herbal formula gui zhi fu ling wan improves semen quality Thirty-seven infertile patients with varicocele were treated with Guizhi-Fuling-Wan (7.5 g/day) for at least 3 months. Before and after the administration, semen qualities such as sperm concentration and motility were examined, and the varicocele was graded. A varicocele disappearance rate of 80% was obtained with 40 out of 50 varicocele, and improvement of sperm concentration and motility were found in 71.4% and 62.1% of patients, respectively. From these results, Guizhi-Fuling-Wan is considered to be effective for circulation disorders in varicocele as well as semen quality. Reference Ishikawa et al. (1996) Effects of guizhi-fuling-wan on male infertility with varicocele. Am J Chin Med, 24(3-4):327-31 (ISSN: 0192-415X).