Acupuncture better than exercise for women with PCOS
The primary outcome measure changes in the concentration of total testosterone (T) at week 16 determined by gas and liquid chromatography-mass spectrometry was analyzed by intention to treat.
Secondary outcome measures were changes in menstrual frequency; concentrations of androgens, estrogens, androgen precursors, and glucuronidated androgen metabolites; and acne and hirsutism. Outcomes were assessed at baseline, after 16 wk of intervention, and after a 16-wk follow-up.
After 16 wk of intervention, circulating T decreased by 25%, androsterone glucuronide by 30%, and androstane-3,17-diol-3-glucuronide b y28% in the electric-acupuncture group (P 0.038, 0.030, and 0.047, respectively vs. exercise); menstrual frequency increased to 0.69/month from 0.28 at baseline in the electric-acupuncture group (P 0.018 vs. exercise).
After the 16-wk follow-up, the acne score decreased by 32% in the electric-acupuncture group (P 0.006 vs. exercise).
Jedel et al. (2011) Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhea in women with polycystic ovary syndrome: a randomized controlled trial. Am J Physiol Endocrinol Metab 300: E37–E45.